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Conducting Effective Global Anti–Money Laundering Investigations in a Complex Regulatory Environment

May 2026Money LaunderingPharmaceutical

Abstract

Global anti–money laundering (AML) investigations present complex operational and regulatory challenges driven by cross-border transactions, fragmented data sources, varying legal regimes, data protection and privacy requirements, and cultural barriers to information sharing. These challenges are further compounded by jurisdictional limitations that may restrict direct cross-border inquiries and require reliance on regulator-to-regulator coordination. Effective global investigations therefore demand a structured, risk-based approach that balances investigative rigor with legal and regulatory permissibility across jurisdictions. This paper outlines leading practices for conducting global AML investigations, including the establishment of clear governance and escalation protocols, preservation of evidence, identification of beneficial ownership, and mapping of transactional flows across multiple jurisdictions. It emphasizes alignment with international standards such as the Financial Action Task Force (FATF) Recommendations and guidance from the U.S. Department of Justice, highlighting the importance of investigative independence, comprehensive documentation, and proportionate remediation. Particular attention is given to the practical challenges of obtaining information in jurisdictions subject to data protection frameworks and regulatory gatekeeping, underscoring the need for early legal engagement and structured escalation pathways. The analysis also considers the role of cross-border information-sharing mechanisms, including supervisory cooperation and mutual legal assistance frameworks, when direct investigative access to information is constrained. Ultimately, a well-executed global AML investigation is positioned not merely as a reactive response to potential misconduct, but as a strategic capability that strengthens organizational resilience, reinforces ethical culture, and mitigates legal, financial, and reputational risk in an increasingly interconnected regulatory environment.

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Authors

Fabiana Lacerca-Allen

Chief Compliance Officer, Cipla, USA

Kwanza Burney

Compliance & Risk Professional | M.S.L. Candidate (Fordham Law), Fordham University School of Law, USA

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